Potential therapeutic targets in obstructive sleep apnoea

Obstructive Sleep Apnoea Syndrome

Paediatric obstructive sleep apnoea.

Department of Otolaryngology, James Cook University Hospital, Middlesbrough TS4 3BW Department of Paediatric Otolaryngology, Royal Hospital for Sick Children, Glasgow G3 8SJ Department of Paediatric Respiratory Medicine, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP Department of Anaesthesia, James Cook University Hospital, Middlesbrough TS4 3BW Correspondence to: S Powell steven_m_powe...

Obstructive Sleep Apnoea Syndrome

Obstructive sleep apnoea.

Obstructive sleep apnoea in adults.

Obstructive sleep apnoea (OSA) is characterised by repetitive closure of the upper airway, repetitive oxygen desaturations and sleep fragmentation. The prevalence of adult OSA is increasing because of a worldwide increase in obesity and the ageing of populations. OSA presents with a variety of symptoms the most prominent of which are snoring and daytime tiredness. Interestingly though, a signif...